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5C18-AR-II column

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The majority of chromatographers use reversed phase silica-based HPLC columns due to their excellent retention characteristics, high theoretical plate number, good cost-performance and ease of use. C18 or ODS reversed phase columns are the most general and popular types. Monomeric and polymeric types are available differing considerably in their retention characteristics.

Nacalai has been offering the monomeric type COSMOSIL 5C18-MS and the polymeric type COSMOSIL 5C18-AR columns, both well received by many chromatographers due to their excellent performance. However, the COSMOSIL 5C18-AR-II can be used for a wider range of compounds than other polymeric types of columns already in use.

Material characteristics

COSMOSIL 5C18- AR-II
Silica gel high purity porous spherical silica
Average particle size 5m
Average pore size approx. 120
Specific surface area approx. 300m2/g
Stationary phase polymeric octadecyl group
End capping treatment near-perfect treatment
Carbon content approx. 17%
Characteristics
The COSMOSIL 5C18-AR-II packed column features a polymeric and near-perfectly end capped type of C18 reversed phase material that employs an ultra-pure silica gel low in metal impurities. In addition, it has stronger acid resistance than the COSMOSIL 5C18-AR. The COSMOSIL 5C18-AR-II column is especially effective for the separation of chelating compounds as well as both acidic and basic compounds.
This series of columns is also highly recommended for a wide range of applications particularly in situations where monomeric-type column (for instance, COSMOSIL 5C18-MS-II) is not as effective as expected.
Acid resistance
The acid resistance of Cosmosil 5C18-AR-II is much improved compared with 5C18-AR. It retains high performance even in case of acidic mobile phase used to separate proteins and peptides.
Ordering information
PRODUCT NAME SIZE CODE No. END-FITTING
COSMOSIL 5C18-AR-II Guard Column 4.6mmI.D.10mm 38141-61 Waters type
10mmI.D.20mm 38148-91
COSMOSIL 5C18-AR-II Packed Column 4.6mmI.D.50mm 38142-51
4.6mmI.D.100mm 38143-41
4.6mmI.D.150mm* 38144-31
4.6mmI.D.250mm* 38145-21
6mmI.D.150mm 38146-11
6mmI.D.250mm 38147-01
COSMOSIL 5C18-AR-II Packed Column 10mmI.D.250mm 38149-81
20mmI.D.250mm* 38150-41
COSMOSIL 5C18-AR-II Packed Column 2.0mmI.D.150mm* 37992-51
*Screw-in type column is available.

 

 

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