The COSMOSIL PE-MS columns (phenylethyl functional group)
and the COSMOSIL CN-MS columns (cyanopropyl functional
group) possess a secondary separation mode (π-π
interaction). These columns are highly recommended for situations
where a C18 or other alkyl chains cannot separate
isomers and other compounds of structural similarity.
Material characteristics
5PE-MS
5CN-MS
Silica gel
high purity spherical porous silica
Average particle size
5µm
Average pore size
approx. 120Å
Specific surface area
approx. 300m²/g
Stationary phase
phenylethyl group
cyanopropyl group
End capping treatment
near-perfect treatment
Carbon content
approx. 10%
approx. 7%
Analysis of mono-substituted
benzenes
The COSMOSIL PE-MS shows slightly longer retention time for
compounds such as nitrobenzenes, which have electron acceptors, or
electron donor compounds (such as anisole). This suggests that
COSMOSIL PE-MS may be effective for the analysis of the compounds,
which cannot be separated by a C18 column.
Analysis of dinitrobenzenes
COSMOSIL PE-MS and COSMOSIL CN-MS separate those dinitrobenzene
isomers which cannot be separated by C18 columns. Ordering information
