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Cosmosil and Cosmogel HPLC columns and packing materials

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Fast LC Columns

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Fast LC columns (4.6mm I.D.50mm) packed with 3m totally porous spherical packing materials provides more than 5,000 theoretical plates. The column length is one fifth that of 250mm columns. The analysis time of Fast LC 4.6mm I.D.50mm column becomes one fifth that of 4.6mm I.D.250mm column since analysis time is in general proportional to column length. The necessary time for the column equilibrium also becomes shorter. Other benefits of using Fast LC columns are reduced solvent consumption and improved detection limits.
Material characteristics

3C18-MS-II 3C18-AR-II 3SL-II
Silica gel high purity spherical porous silica
Average particle size 3m
Average pore size approx. 120
Specific surface area approx. 300m2/g
Stationary phase monomeric type polymeric type -
End capping treatment near-perfect treatment -
Carbon content approx. 16% approx. 17% -
Recommended operating procedures
The use of a COSMOSIL Pre-Filter (1m) between injector and column is highly recommended in order to prevent column clogging. It should also be noted that the use of a guard column or a long connecting tube may reduce column efficiency.
Comparison of theoretical plate numbers
In the example analysis of drugs using a COSMOSIL 5C18 and a COSMOSIL 3C18, the Fast LC column is twice as efficient.
Analysis of furans
The COSMOSIL 3C18 provides the same elution profile as the COSMOSIL 5C18-MS does but in one fifth of the time.
Ordering information
PRODUCT NAME SIZE CODE No. END-FITTING
COSMOSIL 3C18-MS-II Packed Column 4.6mmI.D.10mm 38065-71 Waters type
4.6mmI.D.50mm 38066-61
4.6mmI.D.100mm 38067-51
COSMOSIL 3C18-AR-II Packed Column 4.6mmI.D.10mm 38068-41
4.6mmI.D.50mm 38069-31
4.6mmI.D.100mm 38070-91
COSMOSIL 3C18-P-MS Packed Column 4.6mmI.D.10mm 38062-01
4.6mmI.D.50mm 38063-91
4.6mmI.D.100mm 38064-81
COSMOSIL 3SL-II Packed Column 4.6mmI.D.10mm 38059-61
4.6mmI.D.50mm 38060-21
4.6mmI.D.100mm 38061-11

 

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